Natural History of DVT and Reflux       

Prepared by Peter Henke, MD.

Corresponding chapter in Handbook of Venous Disorders: Chapter 17

• Meissner MH, Manzo RA, Bergelin RO, Markel A, Strandness DE Jr. Deep venous insufficiency: the relationship between lysis and subsequent reflux. J Vasc Surg 1993;18:596-605.

PMID: 8411467

Comment: This study elegantly characterizes the resolution of DVT and venous reflux by duplex ultrasonography.

• Meissner MH, Caps MT, Zierler BK, Polissar N, Bergelin RO, Manzo RA, Strandness DE Jr. Determinants of chronic venous disease after acute deep venous thrombosis. J Vasc Surg 1998;28:826-33.

PMID: 9808849

Comment: This study further characterizes how DVT resolve as measured by US, and is now often standard for assessing residual thrombus.